PROTECTING SENSITIVE SKIN
and care to avoid suffering distressing consequences. Although they
rely on different modes of action, both Delisens and Telangyn specifically decrease the alterations induced by sensitive skin, like itching, pain, flushing, redness, dilated capillaries and hyperpigmentation.
Bodyfensine and Thermostressine reinforce the skin’s natural defensive mechanisms along with the response toward stressing situations
that may terminate in cellular damage. Therefore, these peptides ameliorate the comfort of sensitive skin and protect normal skin from the
same disturbing alterations. •
1. Lee SE, Jeong SK, Lee SH. Protease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitis. Yonsei Med J. 51( 6): 808 – 822, 2010.
2. Paus R, Schmelz M, Bíró T et al. Frontiers in pruritus research: scratching the
brain for more effective itch therapy. J Clin Invest. 116( 5): 1174 – 1186, 2006.
3. Dai Y, Moriyama T, Higashi T et al. Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain. J Neurosci. 24( 18): 4293 – 4299, 2004.
4. Culp B, Scheinfeld N. Rosacea: a review. Pharmacy and Therapeutics. 34 (1):
5. Bevins CL, Liu F-T. Rosacea: skin innate immunity gone awry? Nat Med. 13
( 8): 904-906, 2007.
6. Yamasaki K, Nardo A, et al. Increased serine protease activity and cathelicidin
promotes skin inflammation in rosacea. Nat Med. 13 ( 8): 975-80, 2007.
7. Harder J, Schröder JM. Psoriatic scales: a promising source for the isolation of
human skin-derived antimicrobial proteins. J Leukoc Biol. 77: 476-486, 2005.
8. Schneider JJ, Unholzer A, Schaller M, et al. Human defensins. J Mol Med. 83:
9. Nagy I, Pivarcsi A, Koreck A, et al. Distinct strains of Proionibacterium Acnes
induce selective human β-defensin-2 and interleukin- 8 expression in human keratinocytes through toll-like receptors. J Invest Dermatol. 124: 931-938, 2005.
10. Jonak C, Klosner G, Trautinger F. Heat shock proteins in the skin. Int J Cosm
Sci. 28: 233 – 241, 2006.
11. Laplante AF, Moulin V, Auger FA, Landri J, Li H, Morrow G, Tanguay RM,
Germain L. Expression of heat shock proteins in mouse skin during wound healing.
J Histochem & Cytochem. 46( 11): 1291 – 1301, 1998.
12. Fargnoli J, Kunisada T, Fornace AJ, Schneider EL, Holbrook NJ. Decreased
expression of heat shock protein 70 mRNA and protein after heat treatment in cells
of aged rats. Proc Natl Acad Sci USA. 87: 846 850, 1990.
More info: Caroline Keller, customer relations and marketing
manager, Lipotec LLC, 22 Hudson Place – Suite 4N, Hoboken, NJ
07030 US; Email: firstname.lastname@example.org; Tel. (201) 850-1213;
Fax: (201) 850-1212; Website: www.lipotec.com