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today’s market demand for more natural and environmentally friendly
cosmetics and personal care products. The key to making substitutions
of traditional synthetic ingredients with today’s natural alternatives is
to evaluate their potential impact on, and their interaction with, other
components in the formulation as an early step in the formulating
process. Some traditional ways of doing things may need to be adjusted or modified slightly to accommodate these natural ingredients,
including natural antimicrobials. This early integration into the formulating process will ensure product stability from both a traditional
chemical perspective, as well as a microbiological perspective. The
cosmetic formulator is no longer limited to traditional synthetic preservatives like parabens, isothiazolinones and formaldehyde donors.
They now have a number of effective natural antimicrobial tools in
their formulating toolbox from which to choose. •
1. Cowan, M.M. 1999. Plant products as antimicrobial agents. Clinical
Microbiology Reviews 10: 564-582.
2. Trombetta, D., F. Castelli, M.G. Sarpietro, V. Venuti, M. Cristani, C. Daniele,
A. Saija, G. Mazzanti and G. Bisignano. 2005. Mechanisms of antibacterial action of three monoterpenes. Antimicrobial Agents and Chemotherapy
3. Cushnie,T.P.T. and A.J. Lamb. 2005. Antimicrobial activity of flavonoids.
International Journal of Antimicrobial Agents 26:343-356.
4. Huang, W.C.,T.H. Tsai, L. T. Chuang, Y.Y. Li, C.C. Zouboulis and P.J. Tsai.
2014. Anti-bacterial and anti-inflammatory properties of capric acid against
Propionibacterium acnes: A comparative study with lauric acid. Journal of
Dermatological Science. 73:232-240.
5. Nakatsuji, T., M.C. Kao, J. Y. Fang, C.C. Zouboulis, L. Zhang, R.L. Gallo and C.M.
Huang. 2009. Antimicrobial property of lauric acid against Propionibacterium
acnes: Its therapeutic potential for inflammatory Acne vulgaris. Journal of
Investigative Dermatology 129( 10):2480-2488.
6. Thomas, E.L. and T.M. Aune. 1978. Lactoperoxidase, peroxide, thiocyanate
antimicrobial system: Correlation of sulfhydryl oxidation with antimicrobial
action. Infection and Immunity 5:456-463.
7. Bosch, E.H>, H.Van Doorne, and S. De Vries. 2000. The lactoperoxidase system:
The influence of iodide and the chemical and antimicrobial stability over the
period of about 18 months. Journal of Applied Microbiology 89:215-224.
8. Settanni, L. and A. Corsetti. 2008. Application of bacteriocins in vegetable food
biopreservation. International Journal of Food Microbiology 121: 123-138.
More info: Active Concepts LLC, Lincolnton, NC,
Tel: 704-276-7100; Email: firstname.lastname@example.org;
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