Anti-Aging & Cosmeceutical Corner
THE ANTi-AGiNG BENEFiTS
OF HyALURONiC ACiD
GE TTING OLDER doesn’t necessarily mean looking old. The idea of growing old just doesn’t creep
into the minds of many baby boomers,
who are under pressure to look good all
the time. New anti-aging actives formulated in creams and serums make consumers feel increasingly more youthful
than their actual age as their outer appearances reflect their inner youthfulness. The ever-increasing growth in
new products designed to prevent the
skin from aging has attracted consumers in droves to the vibrant anti-aging
This column will detail the benefits
of hyaluronic acid, which is found naturally in our own skin cells. I’ll answer
two key questions, namely: how do we
keep our skin youthful looking and how
can we undo the damage of time?
Hyaluronic acid’s name is derived from the Greek word for glass
(hyalos) which accurately describes
Navin M. Geria
Senior Technical Advisor
Doctors Skin Prescription
Navin Geria, ex-Pfizer Research Fellow, is senior technical advisor and principal of the dermatological research
company, Doctors Skin Prescription (DSP), Boston,
founded by dermatologist David J. Goldberg M.D.J.D.
and plastic surgeon William P. Adams M.D.F.A.C.S. Geria
has more than 30 years of experience in the personal
care industry and was previously with Clairol, Warner-Lambert, Schick, Bristol-Myers and most recently Spa-Dermaceuticals. He has earned nearly 20 US patents,
has been published extensively and has been both a
speaker and a moderator at cosmetic industry events.
Hyaluronic acid has applications in wrinkle treatments.
its transparent glassy appearance.
Hyaluronic acid (HA), is the most
abundant glycosaminoglycan (GAG)
found in human dermis. It was originally discovered in 1934 by Karl
Meyer and John Palmer who isolated it from bovine vitreous humor.1
In young skin, HA is found at the
periphery and at interfaces of collagen
and elastin fibers. It is thought to help
hold together collagen and elastin in
the proper configuration. Studies have
shown that these connections with HA
are absent in aged skin, which may help
explain the disorganization of collagen
and elastin fibers.2
HA is produced in the human body
and is found in the tissue of all ani-
mals. It is made by bacterial enzyme-
based, bio-fermentation process.
Commercial sources include rooster
combs and chicken cartilage. It is a neg-
atively-charged, sugar-like molecule
of alternating molecules of N-acetyl
glucosamine and glucoronic acid. This
disaccharide molecule is linked to-
gether and belongs to the GAG family
of collagen molecule. HA or sodium HA
is unique because, unlike other types of
collagen, it is not linked to other pro-
teins or sulfur.
HA is non-toxic and non-sensitizing,
and therefore can be safely used for
all skin types and carries no risk of allergic reactions. Dermal fillers enable
dermatologists to inject these natural-ly-occurring components back into the
dermis to restore skin’s volume and
minimize the appearance of wrinkles.